Standard

 

R State Standard         £ Institutionally Developed          College: N/A

 

CHM 1214 – Survey of Organic Chemistry and Biochemistry.

Course Description

Provides an introduction to organic chemistry and biochemistry. This survey will include an overview of the  properties, structure, nomenclature, reactions of: hydrocarbons; alcohols, phenols, ethers, halides, aldehydes, ketones, carboxylic acids, esters, amines, amides; the properties, structure, and function of carbohydrates, lipids, proteins, and enzymes, as well as, intermediary metabolism.  Topics include: basic principles; hydrocarbons; hydrocarbon derivatives; heterocyclic rings and alkaloids; carbohydrates; lipids and fats; proteins; nucleic acids; and intermediary metabolism. Laboratory experience supports classroom learning.

 

Competency Areas

Hours

Basic Principles

Class

4

Hydrocarbons

D. Lab

0

Hydrocarbon Derivatives

P. Lab/O.B.I.

3

Heterocyclic Rings and Alkaloids

Credit

5

Carbohydrates

 

 

Lipids and Fats

 

 

Proteins

 

 

Nucleic Acids

 

 

Intermediary Metabolism

 

 

 

Prerequisite:

CHM 1112 or CHM 1213

Corequisite:

 

 

Course Guide

 

Competency

After completing this section, the student will be able to:

Hours

Class

D.Lab

P.Lab/

O.B.I.

 

 

 

 

Basic Principles

3

0

2

Molecular structure

Define molecular and structural formulas of simple organic compounds.

 

 

 

Distinguish between structural isomers, diastereomers, and enantiomers of simple organic compounds.

 

 

 

Hydrocarbons

8

0

6

Naming compounds

Identify trivial and IUPAC names and structural formulas for alkanes, alkenes, alkynes, aromatics, and alkyl halides.

 

 

 

Reactivity

Identify reactivities for alkanes, alkenes, alkynes, aromatics, and alkyl halides.

 

 

 

Describe the concept of aromaticity and orbital hybridization

 

 

 

Describe a polymerization reaction for an alkene.

 

 

 

Hydrocarbon Derivatives

8

0

6

Naming compounds

Identify trivial and IUPAC names and structures for simple aliphatic compounds containing the following functional groups: alcohols, aldehydes, ketones, carboxylic acids, esters, ethers, amines, amides, hemiacetals, and acetals.

 

 

 

Reactivity

Discuss reactivities and synthesis of the functional groups listed above.

 

 

 

Describe reactions of the functional groups listed above including dehydration and hydrolysis, oxidation and reduction, condensation reactions, and saponification reactions.

 

 

 

Describe and analyze Tollens test.

 

 

 

Describe and analyze Benedict’s test.

 

 

 

Heterocyclic Rings and Alkaloids

2

0

2

Naming compounds

Describe trivial nomenclature and structure of common organic solvents and drugs comprised of a heterocyclic ring structures.

 

 

 

 Reactivity

Describe common biological chemical reactions occurring with drugs that contain heterocyclic ring structures.

 

 

 

Carbohydrates

5

0

3

Naming compounds

Describe trivial nomenclature and structure of common monosaccharides, disaccharides, and complex polysaccharides

 

 

 

 Reactivity

Discuss the physical and chemical properties of carbohydrates.

 

 

 

Lipids and Fats

4

0

3

Naming compounds

Describe the trivial nomenclature and structure of neutral fats, phospholipids, and steroids.

 

 

 

 

Reactivity

Describe the physical and chemical properties of lipids.

 

 

 

Describe the structure, physical properties and physiological function of basic membrane bilayers.

 

 

 

Proteins

5

0

3

Naming compounds

 

Describe the primary, secondary, tertiary and quarternary structure and basic physiological functions of amino acids and proteins.

 

 

 

Discuss peptide and protein synthesis from amino acids by the cell.

 

 

 

Explain enzymes as chemical catalysts.

 

 

 

NUCLEIC ACIDS

3

0

3

Naming Compounds

Describe structure of DNA and RNA.

 

 

 

Describe DNA replication, transcription, and translation.

 

 

 

Discuss the reactivity of nucleic acids.

 

 

 

INTERMEDIARY METABOLISM

2

0

2

Metabolism

Define anabolic and catabolic metabolism.

 

 

 

Explain the role of ATP in cellular energy storage.

 

 

 

Describe glycolysis, the tricarboxylic acid cycle, and oxidative phosphorylation.

 

 

 

 

Suggested Resources

 

Media
(print/audio/
visual/www/
other)

Author

Year

Title: Subtitle

Edition

Location

Publisher/
Publication

pp.

Print

Bettelheim, Brown, & March

2007

Introduction to general, organic and biochemistry.

8th ed.

Belmont CA

Brooks Cole

864

CRC

 

CRC handbook of chemistry and physics.

Any edition.

 

CRC Online Press

2688

Denniston, Katherine J., et. al.

2007

General, organic, and biochemistry.

6th ed.

 

McGraw Hill

968

Wilcox, F. & Wilcox, Mary F.

1994

Experimental organic chemistry: A small scale approach.

2nd ed.

 

Prentice Hall

528

Zubrick, James W.

2007

Organic chem lab survival manual: A student’s guide to techniques.

7th ed.

 

Wiley

368

 

Posted: 10/01/08